Introduction: “My Lobotomy”
PART I Schizophrenia
The Toll of Psychiatric Disorders Is Huge
Schizophrenia Is a Major Neurobiological Challenge in Psychiatry
Schizophrenia is characterized by an unusual array of symptoms
Schizophrenia has a heritable component
RESEARCHERS AT WORK: Stress increases the risk of schizophrenia
An integrative model of schizophrenia emphasizes the interaction of factors
The brains of some people with schizophrenia show structural and functional changes
Antipsychotic medications revolutionized the treatment of schizophrenia
BOX 12.1: Long-Term Effects of Antipsychotic Drugs
PART II Mood Disorders
Depression Is the Most Prevalent Disorder of Mood
Inheritance is an important determinant of depression
The brain changes with depression
A wide variety of treatments are available for depression
SIGNS & SYMPTOMS: Mixed Feelings about SSRIs
Why do more females than males suffer from depression?
Sleep characteristics change in affective disorders
Scientists are still searching for animal models of depression
In Bipolar Disorder, Mood Cycles between Extremes
RESEARCHERS AT WORK: The entirely accidental discovery of lithium therapy
PART III Anxiety Disorders
There Are Several Types of Anxiety Disorders
Drug treatments provide clues to the mechanisms of anxiety
In Post-Traumatic Stress Disorder, Horrible Memories Won’t Go Away
In Obsessive-Compulsive Disorder, Thoughts and Acts Keep Repeating
BOX 12.2: Tics, Twitches, and Snorts: The Unusual Character of Tourette’s Syndrome