Chapter 5 MCQs

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. Which of the following observations does NOT cast doubt on the lipid theory of anaesthesia proposed by Overton and Meyer?

Stereoisomers of anaesthetic drugs display differing anaesthetic potencies even though they possess identical lipid solubilities. correct incorrect

There is a point in a homologous series beyond which anaesthetic potency decreases even though lipid solubility increases. correct incorrect

Only molecules with high volatility exhibit anaesthetic activity. correct incorrect

Some highly lipid-soluble molecules only exhibit one component of anaesthesia (amnesia). correct incorrect

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. Which of the following drugs is NOT obtained from bacteria?

Ketoconazole correct incorrect

Amphotericin B correct incorrect

Nystatin correct incorrect

Gramicidin correct incorrect

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. The ion carrier molecule valinomycin is of little clinical value because

it is a specific potassium ion carrier. correct incorrect

it has a hydrophilic interior and a hydrophobic exterior. correct incorrect

it does not distinguish between mammalian and bacterial cells. correct incorrect

it cannot transport hydrated sodium ions. correct incorrect

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. Carbohydrates have more recently become potential drug targets because

of their structural role. correct incorrect

of their energy storage role. correct incorrect

of their polarity. correct incorrect

of their role in cell recognition. correct incorrect

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. Which of the following drugs inhibits depolymerisation of the protein tubulin?

Vincristine correct incorrect

Colchicine correct incorrect

Vinblastine correct incorrect

Paclitaxel correct incorrect

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. Which of the following drugs does NOT inhibit the transport protein for 5-HT?

Imipramine correct incorrect

Fluoxetine correct incorrect

Levodopa correct incorrect

Amitriptyline correct incorrect

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. Which of the following drugs does NOT block L-type calcium channels?

Lidocaine correct incorrect

Amlodipine correct incorrect

Verapamil correct incorrect

Felodipine correct incorrect

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. Which of the following is NOT a true cytokine?

Interferon correct incorrect

Erythropoietin correct incorrect

Interleukin correct incorrect

Tumour necrosis factor (TNF) correct incorrect

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. Tubocurarine interacts with which type of protein?

Transport protein correct incorrect

Structural protein correct incorrect

Cell signalling protein correct incorrect

Ion channel protein correct incorrect

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. Which of the following drugs that bind to tubulin can be used to treat gout?

Vincristine correct incorrect

Vinblastine correct incorrect

Vindesine correct incorrect

Colchicine correct incorrect