Chapter 10 Multiple Choice Questions

. Which statement about proteins is true?

In the primary structure of a protein, the amino acids are joined together by hydrogen bonds

Each amino acid in a protein is called a residue

Fibrous proteins are soluble in aqueous environments

There is an amino group on both ends of a polypeptide chain

. Consider a protein with the sequence Lys-Ser-Gly-Ala-Ala-Glu-Tyr-Pro-Thr-Val-Phe. Which of the following statements is correct?

This protein could be classified as a decapeptide.

This protein could also be represented by the abbreviation KSGAAEYPTVF.

This protein is mostly comprised of amino acids with polar side chains.

This is an example of a quaternary protein.

. Which of the following is a type of cross-link found in proteins?

Electrostatic interaction

Hydrogen bond

Hydrophobic effect

Disulphide bond

. What is the tertiary structure of a protein?

The overall three-dimensional shape

The sequence of amino acids

The arrangement of subunits

The sequence of nucleotides

. Which of the following factors is most likely to influence how a protein folds into its native conformation?

The establishment of bonding interactions with other parts of the peptide backbone.

The rotation of the peptide bond.

The formation of the maximum possible number of beta-sheets in the final folded structure.

The formation of the maximum number of cis-peptide bonds in the peptide backbone.

. What are the kinetic properties of a competitive inhibitor?

The K_m remains constant in the presence of a competitive inhibitor

The V_max is decreased in the presence of a competitive inhibitor

The K_m is increased in the presence of a competitive inhibitor

The V_max is increased in the presence of a competitive inhibitor

. Which molecules are activated carriers in metabolic reactions?

NADH, NADPH, FADH₂ and acetyl coenzyme A

ADP, ATP and H⁺

NAD⁺, NADP⁺, FAD and coenzyme A

H⁺, NAD⁺ dehydrogenase, O₂ and H₂O

. Which statement about enzymes is true?

Enzymes enable a greater total amount of product to form

Enzymes alter the rate of reaction

Enzymes increase the activation energy required for a reaction to take place

Enzymes alter the position of the reaction equilibrium

. Which of the following represents the enzyme kinetic parameters for non-competitive inhibition?

V_max is not reached, K_m is unchanged, V_max is reduced.

V_max is not reached, K_m decreases, V_max is reduced.

V_max is unaffected, K_m increases.

V_max is not reached, K_m decreases, V_max increases.

. Which of the following statements about atorvastatin is NOT correct?

It is used to treat high blood cholesterol levels.

It is a cholinesterase inhibitor.

It forms hydrogen bonds to the enzyme target.

It forms hydrophobic interactions with the enzyme target.

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