Psychopharmacology 3e Chapter 7 Outline

Acetylcholine

 

Acetylcholine Synthesis, Release, and Inactivation

Acetylcholine synthesis is catalyzed by the enzyme choline acetyltransferase
Many different drugs and toxins can alter acetylcholine storage and release
Acetylcholinesterase is responsible for acetylcholine breakdown
Box 7.1 Pharmacology In Action Botulinum Toxin—Deadly Poison, Therapeutic Remedy, and Cosmetic Aid

Organization and Function of the Cholinergic System

Cholinergic neurons play a key role in the functioning of both the peripheral and central nervous systems
Box 7.2 The Cutting Edge Acetylcholine and Cognitive Function
There are two acetylcholine receptor subtypes: nicotinic and muscarinic