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Return to Psychopharmacology 3e Student Resources
Psychopharmacology 3e Chapter 18 Outline
Affective Disorders: Antidepressants and Mood Stabilizers
Characteristics of Affective Disorders
Major depression damages the quality of life
In bipolar disorder moods alternate from mania to depression
Risk factors for mood disorders are biological and environmental
Animal Models of Affective Disorders
Models of bipolar disorder
Neurochemical Basis of Mood Disorders
Serotonin dysfunction contributes to mood disorders
Norepinephrine activity is altered by antidepressants
Norepinephrine and serotonin modulate one another
Neurobiological Models of Depression
Box 18.1 The Cutting Edge
Epigenetic Modifications in Psychopathology and Treatment
Therapies for Affective Disorders
Monoamine oxidase inhibitors are the oldest antidepressant drugs
Tricyclic antidepressants block the reuptake of norepinephrine and serotonin
Second-generation antidepressants have different side effects
Third-generation antidepressants have distinctive mechanisms of action
Drugs for treating bipolar disorder stabilize the highs and the lows
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