Chapter 2 Self-check Questions and Answers

2.1 Why is it important to keep a track on samples?

  • Awareness of how long processes take
  • Awareness of audit trail
  • Monitor blocks in the system
  • Identify who has handled the specimen

2.2 What are the implications of specimens not being linked correctly to the right patient?

  • Wrong diagnosis for patient
  • Correct patient not being treated
  • Someone well being given incorrect treatment

2.3 Why is clinical information important?

  • Gives a context to the patient’s pathological findings
  • Helps laboratory to guide its investigations
  • Saves wasteful, unnecessary tests

2.4 Why do laboratories use fixatives?

  • Preserves and stabilises tissue
  • Allows subsequent expansive test repertoire
  • Prevents specimen decay by autolysis and putrefaction

2.5 Why is formalin the fixative of choice in most laboratories?

  • Cheap
  • Easily available
  • Penetrates tissue well
  • Allows subsequent testing
  • Effects of fixation can be reversed for certain supplementary tests (i.e. immunocytochemistry)

2.6 Why are specimens decalcified?

  • Removes calcium
  • Makes them suitable for tissue sectioning
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