Section 6.6 Quiz

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. Cytokines secreted during an inflammatory response can drive the expression of subunits of the proteasome, including the 11S subunit and different β subunits with altered specificity, to produce the immunoproteasome.

True correct incorrect

False correct incorrect

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. In the process of MHC class II peptide loading, the protease _____ cleaves the invariant chain but leaves a peptide called the class II-associated invariant chain peptide (CLIP) bound to the peptide-binding groove.

cathepsin S correct incorrect

calreticulin correct incorrect

tapasin correct incorrect

calnexin correct incorrect

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. Which of the following is responsible for driving the expression of costimulatory molecules on a potential antigen-presenting cell (APC)?

Expression of endoplasmic reticulum (ER) chaperones calnexin and calreticulin correct incorrect

Engagement of naïve T cells with the MHC-peptide complex correct incorrect

Cytokines produced during an innate immune response correct incorrect

Release of an MHC family member known as HLA-DM correct incorrect

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