Quiz Content

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. Identify true statements about major histocompatibility complex (MHC) molecules.

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. The α3 domain and β2-microglobulin provides underlying structural support to the peptide-binding groove of MHC class I molecules.

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. The peptide-binding groove of MHC class I molecules interacts and binds to the antigen peptide along its full length.

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. Peptides generated by the destruction of intracellular cytosolic proteins are presented to T-cells via MHC Class II molecules.

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. Which of the following statements are true about the structure of MHC class I molecules?

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. The soluble protein that provides structural support to the protein-binding groove of MHC Class I molecules, along with the α3 domain, using immunoglobulin-like domains is the _____.

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