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Return to Immunology Student Resources
Section 5.8 Quiz
*
not completed
.
Identify the reason for extensive T-cell receptor diversity.
Secretion of IL-7 by developing thymocytes
correct
incorrect
Somatic recombination
correct
incorrect
Lack of allelic exclusion
correct
incorrect
Lack of overexpression of Notch1
correct
incorrect
*
not completed
.
The majority of circulating T cells express _____.
neither αβnor γδT-cell receptor
correct
incorrect
both αβand γδT-cell receptor
correct
incorrect
an αβT-cell receptor
correct
incorrect
a γδT-cell receptor
correct
incorrect
*
not completed
.
T cells in the body that express a γδ T-cell receptor reside mainly within the _____.
thymic medulla
correct
incorrect
bone marrow
correct
incorrect
gut mucosa
correct
incorrect
thymic cortex
correct
incorrect
*
not completed
.
Why is the diversity of variable regions in T cells extensive?
Because recombination of variable segments is random
correct
incorrect
Because of removal rather than addition of P and N nucleotides during recombination
correct
incorrect
Because of repackaging of the β-chain locus into tightly packed chromatin
correct
incorrect
Because a large number of variable segments of D subunits rather than V and J subunits are present
correct
incorrect
*
not completed
.
In the T-cell receptor one properly recombined subunit needs to associate with another randomly recombined subunit.
True
correct
incorrect
False
correct
incorrect
*
not completed
.
Junctional diversity decreases the number of different T-cell receptors to 2.3 × 107.
True
correct
incorrect
False
correct
incorrect
*
not completed
.
Which of the following controls gene arrangement of T-cell receptor loci?
Allelic exclusion
correct
incorrect
Notch signaling pathway
correct
incorrect
MHC restriction
correct
incorrect
Somatic recombination
correct
incorrect
*
not completed
.
An αβ T-cell receptor, when activated, can differentiate into effector T cells that activate a range of adaptive immune responses.
True
correct
incorrect
False
correct
incorrect
*
not completed
.
Identify a true statement about circulating T cells.
They recognize compounds of mevalonate synthesis of different microorganisms.
correct
incorrect
They play a vital role in adaptive immune response.
correct
incorrect
They are responsible for the pattern recognition receptor of the innate immune system.
correct
incorrect
They are responsible for MHC restriction.
correct
incorrect
*
not completed
.
Identify the type of cells that activate a range of other innate or adaptive immune cells, including macrophages, neutrophils, and B cells.
Effector T cells
correct
incorrect
Intraepithelial lymphocytes
correct
incorrect
Thymic epithelial cells
correct
incorrect
Pre-T cells
correct
incorrect
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