Quiz Content

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. Identify possible opportunities for a productive β-chain rearrangement.

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. Recombination of the α-chain locus occurs before the β-chain checkpoint has been passed.

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. Identify the true statement about the pre-T α chain (pTα) in the context of T-cell development.

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. What happens to the large number of thymocytes that do not pass the α- and β-chain checkpoints?

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. Rearrangement of the α chain must be tested to ensure that the chain does not become a subunit of the T-cell receptor.

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. The α chain is tested in the endoplasmic reticulum membrane.

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