Section 5.2-5.3 Quiz

. Hematopoietic stem cells are often characterized by the presence of lineage-specific markers, for example, CD8.

. Human and mouse hematopoietic stem cells have the same cell-surface markers.

. Which of the following cells do all T cells descend from?

. Identify the cells that do NOT descend from lymphoid progenitor cells.

. Which of the following is secreted by thymic epithelial cells as a signaling molecule during T-cell development?

. Which of the following is a cell-surface receptor that interacts with transmembrane ligands on adjacent cells?

. Which of the following has been shown to be vital in committing a lymphoid progenitor to the T-cell lineage?

. Which of the following cells provides Notch ligand to drive commitment to a T-cell fate?

. Which of the following commits thymocytes to T-cell development?

. Which of the following is a domain that translocates into the nucleus of lymphoid progenitor cells, where it activates gene expression required for T-cell differentiation?

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