Section 5.1 Quiz

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. Where do the main events leading to the development of circulating T cells occur?

Lymph nodes correct incorrect

Spleen correct incorrect

Bone marrow correct incorrect

Thymus correct incorrect

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. Undifferentiated lymphocyte precursor cells migrate from the bone marrow and blood to the _____, where T cells develop and mature.

spleen correct incorrect

thyroid correct incorrect

epitope correct incorrect

thymus correct incorrect

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. Which of the following cells present self-antigens to developing thymocytes to test the functionality of the T-cell receptor and to define tolerance to self-molecules?

Dendritic cells correct incorrect

Hassall’s corpuscles correct incorrect

Macrophages correct incorrect

Intraepithelial lymphocytes correct incorrect

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. Identify a true statement about thymus involution.

It begins after the age of 35. correct incorrect

At middle age, thymic cells are no longer present in the body. correct incorrect

It takes place at a rate of approximately 3% per year till the age of 35–45. correct incorrect

At middle age, the rate of thymus involution becomes 6% per year. correct incorrect

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. Describe the roles of the thymus in T-cell development.

plasma cells correct incorrect

cytokines correct incorrect

Hassall’s corpuscles correct incorrect

Peyer's patches correct incorrect