Chapter 1 Self-test questions

Which of the following is common to all mammalian hormones?

They are slow acting.

They are peptides.

They have a single target tissue.

They are carried in blood.

Which is the largest hormone-releasing organ in humans?

Pancreas

Thyroid

Skin

Adrenals

By transplanting a testis back into a castrated cockerel in 1849, Berthold demonstrated…

Transplant rejection.

That there is a neural link between testis and brain.

That there is no link between testis and brain.

That there was an endocrine link between testis and brain.

Which one of the following is true of all steroid hormones? They are:

Made from cholesterol.

Made from the amino acid tyrosine.

Very large molecules (molecular weight >10,000Da).

Very soluble in water.

Which one of the following is true of all peptide hormones?

They are all single chain polypeptides.

They need to be actively secreted by the cell that made them.

They dissolve poorly in blood so need specific transporters.

While circulating in blood they are not actively broken down.

Which of the following statements best describes a steroid hormone when it is bound to a plasma protein?

It is still biologically active.

It is metabolized

Its half-life in blood increases

Its half-life in blood decreases

How do peptide hormones exert their effects on target cells?

By being actively transported into the cell.

By binding to a cell surface receptor.

By binding to an intracellular receptor.

By decreasing production of a second messenger.

How do steroid hormones exert their effects on a target cell?

By being actively transported into the cell.

By binding to a cell surface receptor.

By binding to an intracellular receptor.

By decreasing production of a second messenger.

Which of the following is an example of negative feedback control of hormones?

The action of TRH on the pituitary.

The action of TSH on the thyroid.

The action of thyroid hormones on the liver.

The action of thyroid hormones on the hypothalamus and pituitary.

Which one of the following is true of the action of aldosterone on the renal tubules?

It causes the release of vasopressin (AVP).

It is achieved by aldosterone binding to a cell surface receptor.

It is achieved by increasing the reabsorption of Na+ from urinary filtrate.

It results in a generalized increase in protein synthesis in renal tubular cells.

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