Chapter 3 Outline
Genomics
- Genomics is inextricably linked with advanced methods of information processing
- One overarching goal of genomics is to elucidate the evolution of genes and genomes
- A second overarching goal of genomics is to elucidate the current functioning of genes and genomes
- Genomes must ultimately be related empirically to phenotypes
Top-down versus Bottom-up Approaches to the Study of Physiology
Screening or Profiling as a Research Strategy
The Study of Gene Transcription: Transcriptomics
- Transcription profiling often identifies large numbers of genes that exhibit altered transcription in response to environmental or other conditions
- Transcription profiling reveals that many genes routinely undergo daily cycles of transcription
- Manipulations of protein synthesis can be used to clarify gene function