Genomics

• Genomics is inextricably linked with advanced methods of information processing
• One overarching goal of genomics is to elucidate the evolution of genes and genomes
• A second overarching goal of genomics is to elucidate the current functioning of genes and genomes
• Genomes must ultimately be related empirically to phenotypes

Top-down versus Bottom-up Approaches to the Study of Physiology

Screening or Profiling as a Research Strategy

The Study of Gene Transcription: Transcriptomics

• Transcription profiling often identifies large numbers of genes that exhibit altered transcription in response to environmental or other conditions
• Transcription profiling reveals that many genes routinely undergo daily cycles of transcription
• Manipulations of protein synthesis can be used to clarify gene function

Proteomics

Metabolomics