Chapter 4 Multiple choice Questions

. cAMP is produced by which of the following?

Adenylyl cyclase.

cAMP phosphatase.

Guanylyl cyclase.

Phosphodiesterase.

. Which of the following proteins carries the message from the receptor to adenylyl cyclase?

The receptor does it directly, and no other protein is involved.

Monomeric G protein.

Heterotrimeric G protein.

PKA.

. cAMP is removed from the cytoplasm to create which product?

AMP.

ADP.

ATP.

GMP.

. Which of the following enzymes causes the removal of cGMP from the cytoplasm?

Phosphatase.

Kinase.

Dehydrogenase.

Phosphodiesterase.

. The cleavage of PtdInsP₂ leads to the generation of which of the following?

InsP₃ and cAMP.

InsP₃ and DAG.

InsP₃ and cGMP.

cAMP and DAG.

. PtdInsP₂ is cleaved by which of the following enzymes?

Phosphodiesterase.

Phospholipase A₂.

Phospholipase C.

Phosphatase.

. GEFs are able to activate which of the following?

Kinases.

Monomeric G proteins.

Phosphodiesterases.

Cyclases.

. Son of Sevenless is which of the following?

A receptor.

A phosphatase.

A GAP.

A GEF.

. cAMP is produced from which of the following substrates?

AMP.

ADP.

ATP.

GTP.

. Calmodulin perceives which of the following intracellular signalling components?

cAMP.

Calcium ions.

Chloride ions.

cGMP.

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