Chapter 2 Multiple choice Questions

. A protein that perceives the arrival of a ligand on the outside of a cell is called which of the following?

Transducer.

Receptor.

G protein.

Phosphodiesterase.

. Steroids commonly have their receptor proteins in which of the following cellular locations?

In the plasma membrane.

Outside the cell.

In the mitochondria.

In the cytoplasm.

. G protein coupled receptors are involved in which of the following?

They catalyse the production of cAMP.

They catalyse the production of cGMP.

They interact with heterotrimeric G proteins.

They remove cAMP from the cytoplasm.

. Proteins which facilitate the movement of charged molecules through the membrane are usually referred to as what?

Kinases.

Dehydrogenases.

Ion channels.

Water channels or aquaporins.

. Plasma membrane located receptors can be recycled by which of the following methods?

Direct recycling at the plasma membrane

Endocytosis and recycling through endosomes.

Endocytosis and recycling through lysosomes.

Exocytosis and subsequent recycling through endosomes.

. G protein coupled receptors have how many transmembrane α-helices?

One.

Two.

Seven.

Ten.

. Binding of ligands to receptors can be best characterised by using which of the following?

Scatchard analysis.

Michaelis-Menten kinetics.

Beer Lambert Law.

Nernst Equation.

. Which of the following does not need a membrane bound receptor for perception?

Cytokines.

Nitric oxide.

Adrenaline.

Epidermal growth factor.

. The binding of ligands to receptor tyrosine kinases often cause which of the following?

Dimerisation of receptor subunits.

Trimerisation of receptor subunits.

Cleavage of the receptor subunits.

Movement of the receptors to the mitochondria.

. Dysfunction of the insulin receptor leads to which of the following diseases?

Type 2 diabetes.

Cholera.

Whooping cough.

Covid-19.

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