Chapter 4 Quiz

Quiz Content

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. Refer to the codon table.



Which pair of sequences represents a synonymous mutation?

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. Which compound is not a component of DNA?

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. Which source of variation is most important to evolution?

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. Refer to the figure. The snow goose (Chen caerulescens) has both a blue and a white morph. Inheritance is Mendelian: BB and Bb individuals are blue, while bb individuals are white.



If 23 geese in a population of 142 are white, and 119 are blue, how many of the blue geese would you expect to be carriers of the b allele (i.e., Bb heterozygotes)?

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. Which observation about a population would not violate the assumptions of the Hardy-Weinberg principle?

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. Nonrandom associations between alleles at different loci are referred to by which term?

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. In the figure, the star represents a recent mutation at a gene locus. The letters represent other loci.



Which other locus is most likely to be in linkage disequilibrium with the mutation (all else being equal; assume a sexually reproducing organism)?

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. The mutations shown in the figure involve a transformation of one structure into another structure.



What are these types of mutations called?

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. Refer to the graph showing fitness effects of mutations in the yeast, Saccharomyces cerevisiae.



Which inference is not supported by the data shown in the graph?

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. Sickle cell disease results from a nonsynonymous point mutation of the HBB gene, producing an altered beta chain of hemoglobin. Beta thalassemia is caused by a mutation to the same gene, but instead of an altered beta chain, the final protein is absent or incomplete. Which of these mutations is the most probable cause of beta thalassemia in a patient without a family history of the disease?

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. Humans have 23 chromosome pairs. Other members of the Hominidae, including chimpanzees, gorillas, and orangutans, have 24. What could have caused this difference?

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. A stretch of genome is known to have a constant mutation rate of 106 per generation within a group of species. Two different species within this group are shown to have 16 differences in that stretch of genome. How long have their lineages been separated?

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. A mutation in DNA found in which type of cell would be found in descendants as well as the individual in which the mutation occurred?

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. When we say that mutation is random, we mean that

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. Phenotypic differences that are not based on DNA sequence differences (for example, DNA methylation) can be passed from parent to offspring. This phenomenon is called

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