Chapter 4 Multiple choice questions

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What is epigenetics? Select all correct answers.

The analysis of how genes are related to phenotypes through what is known about experimental embryology correct incorrect

Heritable changes in gene function that are not attributable to alterations in DNA sequence correct incorrect

A form of cellular memory correct incorrect

A phenomenon that affects the transfer of information at both meiotic and mitotic cellular divisions correct incorrect

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Which of the following regulate gene expression? Select all correct answers.

The ribosome correct incorrect

Steroid hormones correct incorrect

Methylation of histones correct incorrect

Serotonin correct incorrect

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What are transacting factors? Select correct answer.

Transacting factors are proteins correct incorrect

Transacting factors are molecules that bind to genomic locations determined entirely by DNA sequence correct incorrect

Transacting factors are molecules that never enter the nucleus of the cell correct incorrect

Transacting factors are molecules that only bind to DNA correct incorrect

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What is non-coding RNA? Select all correct answers.

Nucleic acid that the cell uses to control gene expression correct incorrect

RNA that is transcribed from the non-coding portion of the genome correct incorrect

Part of a molecular code that determines a cell's fate correct incorrect

RNA that is not encoded in DNA correct incorrect

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What are the features of DNA methylation? Select all correct answers.

DNA methylation is a process in which altered DNA is associated with the silencing of gene expression in mammals correct incorrect

DNA methylation has the same function in all species correct incorrect

DNA methylation occurs at the promoters of many mammalian genes correct incorrect

DNA methylation is a phenomenon that affects all mammalian DNA bases equally correct incorrect

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What does chromatin do? Select correct answer.

Chromatin is responsible for DNA packaging correct incorrect

Chromatin regulates the translation of DNA correct incorrect

Chromatin attaches DNA to the nuclear membrane correct incorrect

Chromatin is an inactive component of DNA correct incorrect

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How can epigenetics explain variation in behavior? Select all correct answers.

The modification of chromatin may alter stress-evoked transcriptional and behavioral responses correct incorrect

Enzymes that methylate DNA, imparting an epigenetic mark, could alter gene expression that in turn results in behavioral changes correct incorrect

DNA methylation differences exist between MZ twins, possibly explaining the differences in behavior of genetically identical twins correct incorrect

Genomic imprinting can turn gene expression on or off, explaining why identical sequences may be associated with different gene expression profiles, with downstream effects on behavior correct incorrect

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Which of the following observations can be definitively attributed to epigenetics? Select correct answer.

The inheritance of Mendelian mutations correct incorrect

The inheritance of parenting behavior correct incorrect

Genomic imprinting correct incorrect

Trans-generational inheritance of behavior correct incorrect

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Which of the following are involved in the acquisition of 'omic information? Select all correct answers.

DNA sequencing correct incorrect

RNA sequencing correct incorrect

Protein structure correct incorrect

Chromatin immunoprecipitation correct incorrect

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What is chromosome conformation capture? Select correct answer.

A method of DNA and RNA sequencing correct incorrect

An assessment of how nucleic acid is attached to chromatin correct incorrect

A measures of the number of chromosomes in a cell correct incorrect

A way to determine which sequences in a genome interact physically correct incorrect

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Which of the following human diseases are due to errors in epigenetic regulation? Select all correct answers.

Depression correct incorrect

Schizophrenia correct incorrect

Angelman Syndrome correct incorrect

Prader-Willi Syndrome correct incorrect