Chapter 2 Multiple Choice Questions

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. Which one of the following intermolecular forces is the strongest?

Hydrogen-bonding correct incorrect

Keesom forces correct incorrect

London forces correct incorrect

Debye forces correct incorrect

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. Which one of the following is NOT true of crystalline solids?

They have long range order correct incorrect

They have short range order correct incorrect

They contain a random arrangement of constituents correct incorrect

They have sharp, well-defined melting points correct incorrect

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. Which one of the following is NOT true?
Different polymorphs forms of a drug can have different:

Melting points correct incorrect

Molecular formulae correct incorrect

Solubilities correct incorrect

Crystal habits correct incorrect

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. Which one of the following is NOT a concentration unit?

Mass per volume correct incorrect

Molarity correct incorrect

Milliequivalent correct incorrect

Enthalpy correct incorrect

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. Which one of the following is NOT true?

Drugs can be hydrophilic or hydrophobic correct incorrect

Hydrophobic drugs are easily wetted correct incorrect

Hydrophobic drugs have low solubility in water correct incorrect

Hydrophobic drugs dissolve slowly correct incorrect

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. Which one of the following is NOT true?

Lozenges can be used for local drug delivery correct incorrect

Lozenges can be used for systemic drug delivery correct incorrect

Some lozenges are presented in the form of lollipops correct incorrect

Lozenges are not used for delivery of drugs correct incorrect

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. Which one of the following is NOT true?

Drug release from reservoir systems is controlled by diffusion correct incorrect

Drug release from matrix systems is controlled by diffusion correct incorrect

Drug release from reservoir systems normally follow zero-order kinetics correct incorrect

Drug release from matrix systems normally follow zero-order kinetics correct incorrect

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. Which one of the following is NOT true?

Modified release formulations are most useful for drugs with a long half-life correct incorrect

Modified release formulations can often reduce side-effects correct incorrect

Modified release formulations can improve patient compliance correct incorrect

Modified release formulation can be used for local drug delivery correct incorrect

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. Select the answer that contains one example each of a diluent, disintegrant, binder and glidant.

Lactose, microcrystalline cellulose, sodium starch glycollate and magnesium stearate correct incorrect

Lactose, sodium starch glycollate, PVP and colloidal silica correct incorrect

Calcium carbonate, colloidal silica, talc and magnesium stearate correct incorrect

Calcium carbonate, sodium starch glycollate, talc, microcrystalline cellulose correct incorrect

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. Which one of the following is NOT true?
Tablets are often coated:

to protect the drug from the external environment correct incorrect

to mask bitter tastes correct incorrect

to increase friability correct incorrect

to make swallowing easier correct incorrect