Chapter 1 Multiple Choice Questions

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. Which of the following provides the best definition of pharmaceutics?

It is the study of dosage form design, including associated manufacturing techniques correct incorrect

It is the study of the effect that drugs have on the body correct incorrect

It is the study of the effect that the body has on drugs correct incorrect

It is the study of how drugs can be chemically synthesised correct incorrect

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. Most medicines are made up of the active pharmaceutical ingredient (API) and various excipients. Which one of the following is NOT a possible justification for formulating medicines in this way?

The excipients stabilise the API so that it does not degrade appreciably before administration correct incorrect

The excipients reduce the possibility of the API irritating the body correct incorrect

The API and the excipients each exert a pharmacological effect correct incorrect

The API is too potent to use undiluted correct incorrect

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. Which one of the following is not a route of administration?

Intravenous (IV) correct incorrect

Oral correct incorrect

Topical correct incorrect

Dissolution correct incorrect

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. A rectal suppository is used to treat a fever. This would represent what type of drug delivery?

Parenteral and local correct incorrect

Parenteral and systemic correct incorrect

Enteral and local correct incorrect

Enteral and systemic correct incorrect

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. Which one of the following medicines does not rely on topical drug delivery?

Nasal spray correct incorrect

Anti-dandruff shampoo correct incorrect

Insulin pen correct incorrect

Nicotine patch correct incorrect

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. Which one of the following is not a common dosage form for fentanyl?

Vaporizer correct incorrect

Lollipop correct incorrect

Transdermal patch correct incorrect

IV infusion correct incorrect

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. Which one of the following is an example of the chemical modification of an active pharmaceutical ingredient?

Converting a crystalline API into an amorphous form correct incorrect

Combining a basic API with citric acid to produce the citrate salt of the API correct incorrect

Mixing a poorly soluble API with water to produce a suspension correct incorrect

Mixing a soluble API with water to produce a solution correct incorrect

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. Express 50 mg in kg.

5 x 10^-3 kg correct incorrect

5 x 10^-4 kg correct incorrect

5 x 10^-5 kg correct incorrect

5 x 10^-6 kg correct incorrect

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. A pressure of 1 atm is equivalent to 101325 Pa. Alternatively, this can be expressed as which one of the following?

1.01325 MPa correct incorrect

0.101325 MPa correct incorrect

1013.25 kPa correct incorrect

10.1325 kPa correct incorrect

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. A volume of 10 dm³ may also be expressed as which one of the following?

1 x 10^-3 L correct incorrect

10 L correct incorrect

0.1 m³ correct incorrect

0.001 m³ correct incorrect