Chapter 25 Further reading

Protein synthesis and controlled protein breakdown

• Nirenberg, M. (2004). Historical review: Deciphering the genetic code—a personal account. Trends in Biochemical Sciences, 29, 46–54.

A personal history describing the experiments that enabled the genetic code to be worked out, by one of the 1968 Nobel Prize winners.

• Yonath, A. (2005). Ribosomal crystallography: Peptide bond formation, chaperone assistance and antibiotics activity. Molecules and Cells, 20, 1–16.

A ‘minireview’ by a Nobel Prize winner, relating findings on the structure of ribosomes to various aspects of protein synthesis and folding, and explaining how antibiotics can interfere with ribosome function in a selective fashion.

• Kretzschmar, H., and Tatzelt, J. (2013). Prion disease: a tale of folds and strains. Brain Pathol., 23, 321–32. Review of prion misfolding and prion diseases.

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