Early Development in Sea Urchins

  • Early cleavage
  • Blastula formation
    • The sea urchin fate map

Sea Urchin Gastrulation

  • Ingression of the skeletogenic mesenchyme
  • Epithelial-mesenchymal transition
  • Invagination of the archenteron
    • First stage of archenteron invagination
    • Second and third stages of archenteron invagination

Determination of Sea Urchin Blastomeres

  • Gene regulatory networks and skeletogenic mesenchyme specification
    • Disheveled and β-catenin: specifying the micromeres
  • Specification of the vegetal cells

Early Development in Tunicates  

  • Tunicate cleavage
  • Tunicate gastrulation

Axis Determination in the Tunicate Embryo

  • The tunicate fate map
  • Autonomous and conditional specification of tunicate blastomeres
    • Autonomous specification of the myoplasm: the yellow crescent and macho-1
    • Autonomous specification of endoderm: β-catenin
    • Conditional specification of mesenchyme and notochord by the endoderm
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