Stem Cells: Their Potential and Their Niches

The Stem Cell Concept

  • Division and self-renewal
  • Potency defines a stem cell

Stem Cell Regulation

Pluripotent Cells in the Embryo

  • Meristem cells of the Arabidopsis thaliana embryo and beyond
  • Cells of the inner cell mass in the mouse embryo

Adult Stem Cell Niches in Animals

  • Stem cells fueling germ cell development in the Drosophila ovary

Adult Neural Stem Cell Niche of the V-SVZ

  • The neural stem cell niche of the V-SVZ

The Adult Intestinal Stem Cell Niche

  • Clonal renewal in the crypt

Stem Cells Fueling the Diverse Cell Lineages in Adult Blood

  • The hematopoietic stem cell niche

The Mesenchymal Stem Cell: Supporting a Variety of Adult Tissues

  • Regulation of MSC development

The Human Model System to Study Development and Disease

  • Pluripotent stem cells in the lab
  • Induced pluripotent stem cells
  • Organoids: Studying human organogenesis in a culture dish